Job Description ASR85459.1_DNA_polymerase_II_exonuclease_[Mycobacterium_phage_Cain] Confidence 99.20% Date Mon Jun 7 16:50:03 BST 2021 Rank 38 Aligned Residues 185 % Identity 19% Template c2a1sC_ PDB info PDB header:hydrolase Chain: C: PDB Molecule:poly(a)-specific ribonuclease parn; PDBTitle: crystal structure of native parn nuclease domain Resolution 2.60 Å

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20																.	.	.	.	.	.	.	.	.	30	.	.	.							.	.	.	.	.	.	40
Predicted Secondary structure																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.
Query SS confidence																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.
Query Sequence		A	K	Q	L	I	V	V	D	L	E	T	T	G	L	D	Y	D	T	A	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	P	V	E	V	G	L	L	N	V	D	T	G	.	.	.	.	.	.	E	S	L	Y	F	V	P
Query Conservation																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.
Alig confidence																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.
Template Conservation
Template Sequence		E	A	D	F	F	A	I	D	G	E	F	S	G	I	S	D	F	D	T	P	E	E	R	Y	Q	K	L	K	K	H	S	M	D	F	L	L	F	Q	F	G	L	C	T	F	K	Y	D	Y	T	D	S	K	Y	I	T	K	S	F	N	F
Template Known Secondary structure		T		S									S		S																	T	T	T	B														T	T	T	T
Template Predicted Secondary structure
Template SS confidence
		21	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80
		41	.	.	.									.	.	.	.	.	50	.	.	.	.	.	.				.	.	.	60	.	.	.	.	.	.	.	.	.	70	.
Predicted Secondary structure						.	.	.	.	.	.	.	.													.	.	.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence						.	.	.	.	.	.	.	.													.	.	.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		H	I	T	V	.	.	.	.	.	.	.	.	E	Q	L	A	A	A	D	P	K	A	M	E	.	.	.	I	N	G	Y	Y	E	R	G	L	Y	R	E	A	L	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation						.	.	.	.	.	.	.	.													.	.	.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence						.	.	.	.	.	.	.	.													.	.	.																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		Y	V	F	P	K	P	F	N	R	S	S	P	D	V	K	F	V	C	Q	S	S	S	I	D	F	L	A	S	Q	G	F	D	F	N	K	V	F	R	N	G	I	P	Y	L	N	Q	E	E	E	R	Q	L	R	E	Q	Y	D	P	V	T
Template Known Secondary structure			B						S	S	S	S						B											T	T	T								T	T		B		B											T
Template Predicted Secondary structure
Template SS confidence
		91	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150
							72	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	E	Q	Q	T	A	V	A	W	G	E	V	Q	D	W	L	R	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation		.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		I	P	E	D	Q	K	K	F	I	D	Q	V	V	E	K	I	E	D	L	L	Q	S	E	E	N	K	N	L	D	L	E	P	C	T	G	F	Q	R	K	L	I	Y	Q	T	L	S	W	K	Y	P	K	G	I	H	V	E	T	L	E	T
Template Known Secondary structure				T	T	T																S		S	S											S															S	S	S
Template Predicted Secondary structure
Template SS confidence
		173	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.
																																																			89	90	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	T	F	A	G	S	N	P	A	F	D
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		E	K	K	E	R	Y	I	V	I	S	K	V	D	E	E	E	R	K	R	R	E	Q	Q	K	H	A	K	E	Q	E	E	L	N	D	A	V	G	F	S	R	V	I	H	A	I	A	N	S	G	K	L	V	I	G	H	N	M	L	L	D
Template Known Secondary structure		T	T																																			B	T																	S	S
Template Predicted Secondary structure
Template SS confidence
		233	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.
		100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.				.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.
Predicted Secondary structure																																									.	.	.
Query SS confidence																																									.	.	.
Query Sequence		S	T	I	V	A	R	Q	R	V	T	Y	S	M	P	F	S	P	L	T	V	G	R	V	W	H	H	R	L	A	D	L	A	A	Y	A	A	G	K	L	.	.	.	N	I	D	P	T	E	L	E	G	L	D	A	V	A	E	R	L	G
Query Conservation																																									.	.	.
Alig confidence												.																													.	.	.
Template Conservation												.
Template Sequence		V	M	H	T	V	H	Q	F	Y	C	.	P	L	P	A	D	L	S	E	F	K	E	M	T	T	C	V	F	P	R	L	L	D	T	K	L	M	A	S	T	Q	P	F	K	D	I	I	N	N	T	S	L	A	E	L	E	K	R	L	K
Template Known Secondary structure										T		.				S	S									T	T	T		S	S										S	T	T	T	T	T	T					S								T	T
Template Predicted Secondary structure												.
Template SS confidence
		293	.	.	.	.	.	.	300	.	.		.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.
		157	.	.	160	.	.															.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.
Predicted Secondary structure								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		V	P	V	V	N	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	H	S	A	I	G	D	A	A	A	T	A	F	C	F	D	M	L	R	H	T	A	A	A	H	L
Query Conservation								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence								.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		E	T	P	F	N	P	P	K	V	E	S	A	E	G	F	P	S	Y	Q	L	H	E	A	G	Y	D	A	Y	I	T	G	L	C	F	I	S	M	A	N	Y	L	G	S	F	L
Template Known Secondary structure		S	T	T										T	T	S																											G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		352	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]
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