List of Actual General Chemistry II Lessons for the Biomedical-Focused Approach

• Intermolecular Forces, Solubility and Hydrophobic/Hydrophilic Substances, Kinetic Energy Molecular Distribution, Chemical Reaction Requirements
• Electronegativity and Coulomb's Law, Molecular Geometry and Hybridization, Double Bond Geometry, Condensation Reactions, Triglycerides, Fatty Acids
• Phospholipid Formation and Structure, Surfactants and Soaps, Membrane Structure and Properties, Condensation Reactions, Hydrolysis
• Understanding Henderson-Hasselbalch, Amino Acid Structure, Aromatic Structure, Acid-base Behavior of Amino Acids
• Proteins, Amino Acid Condensation and Protein Hydrolysis Reactions, Peptide Bond Geometry and Resonance, Protein Primary Structure and Disulfide Bonds, Secondary Structure - Alpha Helices and Beta Sheets, Key Interactions for Protein Folding, Prions
• Review and Quiz (Course Competencies)
• Rates of Chemical Reactions; Rate Law; Arrhenius Equation; Experimental Determination of Reaction Order, Rate Constants, and Activation Energy; Arrhenius Plots
• Enzyme Kinetics (Michaelis-Menton and Lineweaver-Burke)
• Nonsteroidal Anti-inflammatory Drugs (NSAIDs): COX-2 Inhibitors, Nonspecific COX Inhibitors
• COX-2 Inhibitors: Molecular Design, Mechanism of Action, Therapeutic Utility, and Side Effects
• Test 1
• Inflammation, Steroids, Zinc Finger Steroid Receptors, Steroidal Anti-Inflammatory Mechanism of Action (MOA):
• DNA, Central Dogma, and Complex Ions
• Synapse, Neurotransmitters
• Thermodynamics and Electrochemistry I
• Thermodynamics and Electrochemistry II
• Sodium/Potassium Pump, Oxidative Phosphorylation
• Quiz, HW7 Problem Set Due
• Review of Thermodynamics, Electrochemistry, and Ion Channels
• Neurotransmitters I
• Neurotransmitters II
• Test #2
• Local and General Anesthetics, Opioids
• Adrenergic Neurotransmitters and Receptors
• Stratospheric Ozone Depletion, Tropospheric Ozone Production
• Thermodynamics and Second Law