Lsn 7: Enzymes as Drug Targets II  (Enzyme Kinetics)

• Michaelis-Menton kinetics
• Write equilibria associated with enzyme-substrate interactions
• Understand how reaction order changes with substrate concentration
• Be able to use the Lineweaver-Burke relationship to calculate V_max, turnover number, and K_M
• Understand the significance of K_M; understand the relation of K_M to enzyme-substrate complex stability and to maximum reaction rate