1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	D	H	T	L	S	L	D	I	A	G	E	V	G	A	D	P	A	D	V	A	E	A	A	A	R	A	A	E	H	A	K	A	A	A	A	E	L	L	L	D	M	V	P	A	E	S	Y	D	V	L	Y	A	A	L	S	A	R	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?							?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	Y	E	R	N	G	G	R	Q	L	R	M	F	V	P	G	K	P	A	P	Q	G	S	K	D	F	M	G	F	K	K	A	P	E	G	S	P	P	G	T	R	G	P	A	I	L	K	E	S	S	A	A	V	G	P	W	R	E	R	I
Secondary structure
SS confidence
Disorder				?																	?	?		?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?			?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	L	A	S	A	D	A	M	L	S	A	G	L	P	V	L	D	K	K	Y	P	V	R	A	S	L	T	F	V	M	P	R	P	S	G	T	P	K	S	Y	T	P	P	A	V	K	R	P	D	L	D	K	L	A	R	A	V	L	D	G
Secondary structure
SS confidence
Disorder													?			?																		?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.
Sequence		L	T	D	V	V	W	L	D	D	S	Q	V	D	D	L	H	A	R	K	V	L	A	E	L	S	Q	Q	P	G	C	H	M	R	I	A	S	P	G	W	G	D	E	A	I	A	A	W	Q	A	A	N	G	G	A	A	H	V
Secondary structure
SS confidence
Disorder																																																	?	?		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 25%) Alpha helix ( 30%) Beta strand ( 21%)

Rank Aligned region

PDB 1q8r chain A Region: 69 - 218 Aligned: 114 Modelled: 150 Confidence: 99.6% Identity: 32% Fold: Bacillus chorismate mutase-like Superfamily: Holliday junction resolvase RusA Family: Holliday junction resolvase RusA Phyre2 PDB 6idy chain C Region: 50 - 91 Aligned: 42 Modelled: 42 Confidence: 33.3% Identity: 26% PDB header:lipid binding protein Chain: C: PDB Molecule:lipase aflb; PDBTitle: crystal structure of aspergillus fumigatus lipase b Phyre2 PDB 5zc1 chain A Region: 149 - 217 Aligned: 67 Modelled: 69 Confidence: 26.4% Identity: 21% PDB header:hydrolase inhibitor Chain: A: PDB Molecule:cystatin-1; PDBTitle: x-ray diffraction analysis of the csstefin-1 Phyre2 PDB 7crc chain B Region: 91 - 124 Aligned: 34 Modelled: 34 Confidence: 23.0% Identity: 15% PDB header:plant protein Chain: B: PDB Molecule:nad+ hydrolase (nadase); PDBTitle: cryo-em structure of plant nlr rpp1 tetramer in complex with atr1 Phyre2 PDB 3vh5 chain D Region: 21 - 44 Aligned: 24 Modelled: 24 Confidence: 20.0% Identity: 63% PDB header:dna binding protein Chain: D: PDB Molecule:cenp-x; PDBTitle: crystal structure of the chicken cenp-t histone fold/cenp-w/cenp-2 s/cenp-x heterotetrameric complex, crystal form i Phyre2 PDB 3w06 chain A Region: 51 - 79 Aligned: 26 Modelled: 29 Confidence: 12.7% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:hydrolase, alpha/beta fold family protein; PDBTitle: crystal structure of arabidopsis thaliana dwarf14 like (atd14l) Phyre2 PDB 4wnx chain A Region: 136 - 156 Aligned: 21 Modelled: 21 Confidence: 12.4% Identity: 24% PDB header:laminin binding protein Chain: A: PDB Molecule:netrin-4; PDBTitle: netrin 4 lacking the c-terminal domain Phyre2 PDB 1hyw chain A Region: 43 - 72 Aligned: 30 Modelled: 30 Confidence: 12.0% Identity: 30% Fold: gpW/XkdW-like Superfamily: Head-to-tail joining protein W, gpW Family: Head-to-tail joining protein W, gpW Phyre2 PDB 6u08 chain H Region: 47 - 76 Aligned: 30 Modelled: 30 Confidence: 11.5% Identity: 37% PDB header:toxin Chain: H: PDB Molecule:dddi; PDBTitle: double-stranded dna-specific cytidine deaminase type vi secretion2 system effector and cognate immunity complex from burkholderia3 cenocepacia Phyre2 PDB 4plo chain A Region: 136 - 156 Aligned: 21 Modelled: 21 Confidence: 11.3% Identity: 48% PDB header:protein binding Chain: A: PDB Molecule:netrin-1; PDBTitle: crystal structure of chicken netrin-1 (ln-le3) in complex with mouse2 dcc (fn4-5) Phyre2 PDB 4aqs chain A Region: 136 - 156 Aligned: 21 Modelled: 21 Confidence: 11.1% Identity: 24% PDB header:cell adhesion Chain: A: PDB Molecule:laminin subunit beta-1; PDBTitle: laminin beta1 ln-le1-4 structure Phyre2 PDB 4khb chain F Region: 70 - 77 Aligned: 8 Modelled: 8 Confidence: 10.3% Identity: 38% PDB header:transcription/replication Chain: F: PDB Molecule:uncharacterized protein pob3n; PDBTitle: structure of the spt16d pob3n heterodimer Phyre2 PDB 1e5q chain A domain 2 Region: 70 - 92 Aligned: 23 Modelled: 23 Confidence: 10.0% Identity: 30% Fold: FwdE/GAPDH domain-like Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family: Homoserine dehydrogenase-like Phyre2 PDB 6los chain H Region: 78 - 94 Aligned: 17 Modelled: 16 Confidence: 8.9% Identity: 35% PDB header:signaling protein Chain: H: PDB Molecule:collagen model peptide, type i, alpha 1; PDBTitle: crystal structure of mouse pedf in complex with heterotrimeric2 collagen model peptide. Phyre2 PDB 3b6n chain A Region: 169 - 205 Aligned: 37 Modelled: 37 Confidence: 8.8% Identity: 24% PDB header:lyase Chain: A: PDB Molecule:2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthase; PDBTitle: crystal structure of 2c-methyl-d-erythritol 2,4-cyclodiphosphate2 synthase pv003920 from plasmodium vivax Phyre2 PDB 5gn0 chain H Region: 151 - 169 Aligned: 19 Modelled: 19 Confidence: 8.5% Identity: 42% PDB header:transcription Chain: H: PDB Molecule:ww domain-containing transcription regulator protein 1; PDBTitle: structure of taz-tead complex Phyre2 PDB 6m9k chain D Region: 166 - 189 Aligned: 24 Modelled: 24 Confidence: 8.4% Identity: 25% PDB header:hydrolase Chain: D: PDB Molecule:recombination protein bet; PDBTitle: crystal structure of lambda exonuclease in complex with the red beta2 c-terminal domain Phyre2 PDB 6los chain G Region: 78 - 93 Aligned: 16 Modelled: 16 Confidence: 7.7% Identity: 38% PDB header:signaling protein Chain: G: PDB Molecule:collagen model peptide, type i, alpha 1; PDBTitle: crystal structure of mouse pedf in complex with heterotrimeric2 collagen model peptide. Phyre2 PDB 2eze chain A Region: 80 - 95 Aligned: 15 Modelled: 16 Confidence: 7.5% Identity: 40% PDB header:dna binding protein/dna Chain: A: PDB Molecule:high mobility group protein hmg-i/hmg-y; PDBTitle: solution structure of a complex of the second dna binding2 domain of human hmg-i(y) bound to dna dodecamer containing3 the prdii site of the interferon-beta promoter, nmr, 354 structures Phyre2 PDB 1dgs chain A domain 2 Region: 193 - 218 Aligned: 26 Modelled: 26 Confidence: 7.4% Identity: 23% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: DNA ligase/mRNA capping enzyme postcatalytic domain Phyre2 1 d1q8ra_ 2 c6idyC_ 3 c5zc1A_ 4 c7crcB_ 5 c3vh5D_ 6 c3w06A_ 7 c4wnxA_ 8 d1hywa_ 9 c6u08H_ 10 c4ploA_ 11 c4aqsA_ 12 c4khbF_ 13 d1e5qa2 14 c6losH_ 15 c3b6nA_ 16 c5gn0H_ 17 c6m9kD_ 18 c6losG_ 19 c2ezeA_ 20 d1dgsa2 21 22 23 24 25 26 27 28 29 30 31 32 33 34