CHEM 313 - Quantitative Analysis, 20305, sec. 001, 3.0 Credit Hr., Spring 2024

Meeting Time/Location:		12:30 - 1:45 TR/Sims 111
Professor:	Dr. Cliff Calloway	(callowayc@winthrop.edu)
	Office:	312-B Sims Science Building
	Hours:	MTR, 10:00-12:00 and by appointment
	Phone:	4945 (off campus: 803-323-4945); Cell: (803)329-4582

Course Goals:  Chemical analysis methods are used to determine chemical, physical and/or structural properties of a substance. Methods used to provide the identity of a substance or structural information, are called qualitative chemical analysis methods. Methods that determine the amount of a substance are called quantitative chemical analysis methods. In this course, we will be primarily concerned with these quantitative methods as well as techniques used to separate components of a mixture.  We will look at the underlying chemical principles and phenomena upon which these methods are based. Quantitative analysis is generally the first course students see in the field of analytical chemistry...one of the five main areas of chemistry.

University Level Competencies: Winthrop University's faculty have adopted a set of four University Level Competencies (ULCs) that describe the qualities our students develop during their studies at Winthrop. It's easy to see that this course involves solving problems and developing good communication skills.  However, you will also learn about the responsibilities of chemists to the greater good of our planet and society, as well as the global nature of chemistry.  Within our discussions of chemical analysis, applied to the environment, health and materials we use every day, I think you will find this course fits well with all four competencies.

Competency 1: Winthrop graduates think critically and solve problems. Winthrop University graduates reason logically, evaluate and use evidence, and solve problems. They seek out and assess relevant information from multiple viewpoints to form well-reasoned conclusions. Winthrop graduates consider the full context and consequences of their decisions and continually reexamine their own critical thinking process, including the strengths and weaknesses of their arguments.

You will be using sophisticated mathematical and descriptive methods to solve problems found in environmental, pharmaceutical, biomedical, energy, food, forensic and electronic fields, for example.

Competency 2: Winthrop graduates are personally and socially responsible. Winthrop University graduates value integrity, perceive moral dimensions and achieve excellence. They take seriously the perspectives of others, practice ethical reasoning, and reflect on experiences. Winthrop graduates have a sense of responsibility to the broader community and contribute to the greater good.

Chemistry touches 95% of everything we use, daily. Chemists need to be critically aware of industry impacts on the environment and human health.

Competency 3: Winthrop graduates understand the interconnected nature of the world and the time in which they live. Winthrop University graduates comprehend the historical, social, and global contexts of their disciplines and their lives. They also recognize how their chosen area of study is inextricably linked to other fields. Winthrop graduates collaborate with members of diverse academic, professional, and cultural communities as informed and engaged citizens.

Chemistry is a global enterprise with many industries located around the world that impact our quality of life. Chemistry is a core topic, touching most fields of interest from science, to art, to technology.

Competency 4: Winthrop graduates communicate effectively. Winthrop University graduates communicate in a manner appropriate to the subject, occasion, and audience. They create texts including but not limited to written, oral, and visual presentations that convey content effectively. Mindful of their voice and the impact of their communication, Winthrop graduates successfully express and exchange ideas.

Science, in general, is difficult to understand, so correct, clear and effective communication methods are key. Peer review is fundamental to scientific communications.

Student Learning Outcomes: By the end of this course, you should be able to:

• distinguish between quantitative and qualitative methods of analysis
• understand various expressions of concentration, including effective concentration
• understand how chemical reactions are used to provide quantitative information
• understand how equilibrium and kinetic concepts relate to quantitative measurements
• apply rigorous problem-solving skills to complex problems involving stoichiometry, equilibrium, acid-base chemistry, complex formation, electrochemical measurements, spectrophotometry and chromatography
• distinguish experimental methods that answer questions of elemental versus molecular chemical analysis
• process data from calibration curve, standard addition, and internal standard methods of quantitative analysis
• understand the use of analytical standards and calibration, experimental sources of error and interference
• apply computer spreadsheet programs to data analysis and problem-solving

Course Prerequisites: Grades of C or better in CHEM 301 (Organic Chemistry I), MATH 201 (Calculus I), and PHYS 211 or 201 (Physics I) are required before attempting this course. You are expected to have a firm grasp on the principles introduced in these courses. We move at a brisk pace and will not have the time to review concepts from these courses.

Course Co-requisites: You should also be registered for CHEM 312 (Introductory Chemometrics) and CHEM 314 (Quantitative Analysis Lab).

Attendance: You are expected to attend each class meeting for the scheduled time. This will help you to concentrate on the appropriate material and reinforce the assigned readings and problems.

Course Requirements: You must bring pencil, paper and scientific calculator to each class. Cell phone calculators are not acceptable. You may find your textbook helpful.  Be sure you know how to do mean, standard deviation, logarithms (base 10 & base e, including inverses), as well as least squares (i.e. - linear slope & intercept) with your calculator.  You are required to complete: 1) four in-class exams, 2) thirteen homework assignmewnts and 3) a standardized, cumulative final exam as indicated on the lecture schedule. For your convenience and calendar, dates for the in-class exams and final exam are:

February 1 (Exam I - Ch. 0,1,6,8)

March 5 (Exam II - Ch. 23,24, 25)

March 28 (Exam III - Ch. 18,19, 21)
April 16 (Exam IV - Ch. 14,15)

Thursday, April 25 11:30 am (Final Exam - Cumulative/Standardized)

Official Textbook: Harris, D.C.; Lucy, C.A  Quantitative Chemical Analysis, 10^th edition, Macmillan Learning, New York. 2020. Other analytical chemistry textbooks are available in the library and are helpful as additional practice.

Homework Assignments: Quantitative Analysis is a course that focuses primarily on numerical problem solving.  To be successful, this often requires a substantial amount of practice.  Homework problems have been assigned for each chapter through Achieve to help you master the skills.  Recommended additional problems from the textbook are also listed on the Homework tab.

In-class Exams: Each in-class exam consists of an in-class portion (multiple choice questions and open-ended problems) and a take-home Excel problem that is due with the in-class portion.  You need a calculator for each in-class exam and may NOT share. Formula sheets, tables, and scratch paper will be provided. You're expected to show all work to receive full credit. Lack of, or incorrect units is an automatic one-point deduction. The take-home Excel problem (no collaboration allowed) must have proper format features and formula documentation to receive credit. Our textbook has numerous spreadsheets showing how to properly document a spreadsheet.

Final Exam:  The final exam is a cumulative, standardized exam produced by the American Chemical Society.  It consists of 50 multiple choice questions.  Formula sheets, tables and scratch paper will be provided.  Each answer is worth 2.5 points, so scoring above 100 is possible. 

Grading: To determine your letter grade, the average of your four in-class exam scores will contribute 50% to your course grade total. The average of your homework assignments will contribute 30% and the final exam will contribute 20%. Letter grades will then be assigned from the sum as follows: 94-100%: A; 90-93%: A-; 86-89%: B+; 82-85%: B; 78-81%: B-; 74-77%: C+; 70-73%: C; 66-69%: C-; 62-65%: D+; 58-61%: D; 55-57%: D-

Special notes:

• Your lowest homework grade will be dropped before determining the average.
• If your final exam score is higher than your lowest in-class exam score, I will replace the lowest in-class exam score with the final exam score, then average.
• Missed exams require a written, validated excuse. Illnesses can be validated through the Student Health Services/Doctor. Non-illnesses can be validated through Student Affairs. Once validated, you may either drop the exam (remaining scores will be averaged) or a make-up will be scheduled.  You should keep your documentation....just show or email photo, etc.
• Student Conduct Code: "Responsibility for good conduct rests with students as individuals." Student Handbook: https://www.winthrop.edu/studentconduct/winthrop-university-student-handbook.aspx
• Winthrop University is committed to providing accessible learning experiences and equal access to education for all students. The syllabus is available in alternate formats upon request.  If you are a student with a disability (including mental health concerns, chronic or temporary medical conditions, learning disabilities, etc.) and you anticipate or experience academic barriers due to the condition, please contact the Office of Accessibility (OA) for information on accommodations, registration and procedures. After receiving approval for accommodations through OA, please make arrangements with me as soon as possible to discuss your accommodations so that they may be implemented in a timely manner. OA contact information: accessibility@winthrop.edu: 803-323-3290; Macfeat House.
• Dropping the Course: We will follow the University policy and dates as specified in the Undergraduate Catalog.
• Syllabus change policy; The professor reserves the right to change the syllabus, if circumstances require.
• COVID-19 Statement: Although COVID-19 has reached an endemic phase, it is still important to remain vigilant as we face a recent rise in positive cases. As socially responsible members of this community, everyone is expected to engage in daily health self-monitoring, to stay home (residence hall or off-campus housing) from on-campus class, work, or activities if they begin experiencing any COVID-related symptoms. When experiencing any COVID-related symptoms, students are expected to contact Health Services by completing the QI form in the Patient Portal and respond to the nurse who will contact them with instructions. COVID positive residential students are required to follow their QI plan for 5 days of isolation off-campus so be prepared with a back-up plan as well. By acknowledgement, you agree to Winthrop's expectations of you regarding health monitoring and reporting.

Menu of Topics:

• Overview of Analytical Chemistry and the Process
• Measurements and Concentration Expressions, including Activity
• Chemical Equilibrium (Solubility, Complex Formation and Acid/Base)
• Separations and Chromatography (Gas/Liquid)
• Spectrophotometry (Molecular/Atomic)
• Electrochemistry and Potentiometry